KRAS G12C è un biomarcatore chiave nel NSCLC

La mutazione KRAS G12C è una delle più comuni nel carcinoma polmonare non a piccole cellule (NSCLC).

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The KRAS gene helps to regulate cell proliferation, differentiation, and survival.

KRAS G12C is a specific KRAS mutation that results in the substitution of glycine for cysteine at position twelve of the KRAS protein.

The KRAS G12C mutation is one of the most common non small lung cancer (NSCLC) molecular biomarkers, occurring in 13% of patients from western ...populations.
Biomarker testing can determine if a patient's NSCLC harbors the KRAS G12C mutation.